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KMID : 0882420090760020209
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Korean Journal of Medicine
2009 Volume.76 No. 2 p.209 ~ p.214
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A case of CMV-induced gastric ulcer
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Lee Mi-Jeong
Park Jae-Myung
Cho Yu-Kyung
Lee In-Suk
Kim Sang-Woo
Choi Myung-Gyu
Chung In-Sik
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Abstract
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A 59-year-old female with breast cancer, who had been treated with cancer chemotherapy and radiotherapy, visited the hospital with a 2-week history of epigastric pain. Upper gastrointestinal endoscopy showed multiple ulcers with gastric hypertrophy. In the biopsy specimen, no malignant cells were observed, but some cells were positive on immunochemistry examination for cytomegalovirus (CMV). Ganciclovir was administered for 2 weeks. Her symptoms improved and the immunochemistry finding of a subsequent gastric mucosal specimen was negative. However, the lumen of the gastric antrum was too narrow for the endoscope to pass the pylorus easily. A gastric perforation resulted and was treated with total gastrectomy and esophagojejunostomy, while an endoscopic stent was inserted to allow oral intake. Here, we report a case of gastric ulcer resulting from CMV infection and stenosis as a complication in an immunosuppressant patient. (Korean J Med 76:209-214, 2009)
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KEYWORD
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Cytomegalovirus, Gastric ulcer, Immunosuppression, Stricture
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